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Feature Article: Acute Graft-Versus-Host Disease

Categories: Hematology

October 2004 Volume 2, Issue 10

Javier BolaƱos-Meade, MD, and Georgia B. Vogelsang, MD

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Acute graft-versus-host disease (aGVHD) continues to be a problem in allogeneic transplantation. Recent advances in the understanding of the induction and propagation of GVHD have lead to new transplant strategies and treatment of aGVHD. This overview covers the basic pathophysiology, prophylaxis and treatment of this disorder.